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For families

Your dog was diagnosed. What now?

The essentials on one page: the signs, the tests, the treatment options and what to expect. Bring it to your next appointment and use it to frame questions for your veterinary oncologist.

Nosebleeds (epistaxis)

Often from one nostril, sometimes intermittent.

One-sided nasal discharge

Mucus or pus from one side, sometimes tinged with blood.

Facial swelling or deformity

A bump over the nose or below the eye.

Sneezing and reverse sneezing

Persistent or worsening, not resolved by allergy treatment.

Noisy breathing or snoring

Reduced airflow through one or both nostrils.

Eye changes

Watery eye, discharge, or an eye that bulges on one side.

Pain or reluctance

Pawing at the face, or not wanting the muzzle touched.

Seizures or behavior change

Can occur if the tumor reaches the brain. Seek care right away.

Why one side matters

Allergies and many infections usually affect both nostrils. Signs that stay on one side are a reason to look further.

  1. Exam and history

    Your vet checks airflow through each nostril, the face, eyes, teeth and the lymph nodes under the jaw.

  2. Blood work and clotting tests

    Rules out bleeding disorders, high blood pressure and tick-borne disease as causes of nosebleeds, and checks overall health before anesthesia.

  3. CT scan of the head

    The key test. It shows the tumor's size, bone destruction, and whether it reaches the eye socket or the cribriform plate near the brain. It is also the map used to plan radiation.

  4. Rhinoscopy and biopsy

    A tissue sample, often taken right after the CT, is examined by a pathologist. A biopsy is the only way to confirm the tumor type.

  5. Staging

    Chest imaging and lymph node sampling check for spread. Combined with the CT, this assigns a stage that guides treatment and prognosis.

OptionWhat it involvesTypical scheduleGoal
Stereotactic radiation (SRT / SRS)Very precise, high-dose beams shaped to the tumor, guided by CT. Spares more surrounding tissue.1–5 sessionsTumor control with fewer anesthesia events
Conventional (definitive) radiationLower doses given over many sessions to the tumor and a margin around it.12–20 sessionsLong-term tumor control
Palliative radiationA short course aimed at relieving bleeding, pain and congestion.1–4 sessionsComfort and quality of life
Surgery after radiationRemoval of remaining tumor tissue in selected dogs after radiation.Specialist decisionLonger control in select cases
MedicationsAnti-inflammatories (NSAIDs), some chemotherapies or targeted drugs, and drugs to manage bleeding.OngoingComfort, slow growth
Clinical trialsAccess to new treatments, such as FLASH, immunotherapy or ablation technologies.VariesNew options and new knowledge

SRT vs. SRS

Stereotactic radiosurgery (SRS) delivers the full dose in a single session. Stereotactic radiation therapy (SRT) splits it into a few sessions, usually three. Both need specialized equipment and planning. Find a center.

Side effects

Expect temporary irritation of the nose lining, skin and eyes. Ask about dry eye and cataracts, which can appear later. Stereotactic techniques aim to reduce these effects.

Bars show the range of median survival reported across studies, not the range for individual dogs. Many dogs live well beyond these figures.

What affects the outlook

  • Stage, especially whether the tumor has broken through the cribriform plate
  • Tumor type (carcinoma vs. sarcoma)
  • Whether signs like nosebleeds are present at diagnosis
  • Response to the first course of treatment

Quality of life comes first

Radiation often relieves bleeding and congestion within weeks. Track good days and hard days with your family and your vet. Comfort, appetite and breathing are the best guides.

  • What stage is the tumor, and does it involve the cribriform plate?
  • Is my dog a candidate for stereotactic radiation, conventional radiation, or both?
  • How many anesthesia sessions will treatment need?
  • What side effects should we watch for, during treatment and months later?
  • Are there clinical trials my dog could join?
  • What can we do at home for comfort, nutrition and activity?
  • How will we know whether treatment is working?
  • Is an immunotherapy such as Gilvetmab an option for my dog?
Ask about immunotherapy

Gilvetmab

Gilvetmab is an immune checkpoint inhibitor made for dogs. It targets PD-1, a receptor on T-cells (a type of white blood cell), and blocks it from binding to PD-L1 and PD-L2. Tumors use that connection as a brake on the immune system. Releasing the brake lets the dog's own T-cells recognize and destroy cancer cells.

Ask your oncologist whether Gilvetmab fits your dog's tumor type and stage, and whether it could be paired with radiation.